Author

K. X. Lew

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. T. Saurin· 1 shared R. Foy· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperCancer Biology

A. T. Saurin

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1 paper

Recent·Most cited

The search for CDK4/6 inhibitor biomarkers has been hampered by inappropriate proliferation assays

R. Foy, K. X. Lew, A. T. Saurin

This paper shows that ATP-based proliferation assays overestimate CDK4/6 inhibitor response due to G1 cell overgrowth, and identifies Cyclin D1 and RB1 as potential biomarkers using DNA-based assays.

bioRxiv · Mar 15, 2023Cancer Biology