AICAR induces apoptosis and inhibits migration of prostate cancer cells through an AMPK/mTOR-dependent pathway
C.-C. Su, K.-L. Hsieh, S.-C. Wang, H.-C. Yeh, S.-P. Huang, P.-L. Liu, S.-H. Fang, W.-C. Cheng, K.-H. Huang, F.-Y. Chiu, I.-L. Lin, M.-Y. Huang, C.-Y. Li
This study shows AICAR inhibits prostate cancer cell growth, induces apoptosis, reduces migration, and enhances chemosensitivity via the AMPK/mTOR pathway.
bioRxiv · Nov 19, 2018Cancer Biology