Activation of RIG-I-mediated antiviral signaling triggers autophagy through the MAVS-TRAF6-Beclin-1 signaling axis
K.-S. Inn, N.-R. Lee, J. Ban, N.-J. Lee, C.-M. Yi, J. Choi, H. Kim, J.-K. Lee, J. Seong, N.-H. Cho, J. U. Jung
This study shows that RIG-I activates autophagy via the MAVS-TRAF6-Beclin-1 axis to control viral replication and limit excessive interferon response.
bioRxiv · Jun 6, 2018Immunology