Cbfb2 gene dosage programs the differential lymphoid lineage developmental potential of fetal and adult hematopoietic progenitors
Alyssa Berthelette, Kaelie Newell, Quan M Phan, Ichiro Taniuchi, Joonsoo Kang, Michela Frascoli
This study shows that Cbfb2 gene dosage regulates the developmental potential of hematopoietic progenitors, enabling fetal-like lymphoid lineage generation in adults.
bioRxiv · Mar 5, 2026 · PreprintImmunology