Author

Ichiro Taniuchi

RIKEN Center for Integrative Medical SciencesORCID 0000-0002-9853-9068Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Akinori EndoiD· 1 shared Alyssa BertheletteiD· 1 shared Cheng‐Ming ChuongiD· 1 shared Chengcheng ZouiD· 1 shared Chihiro OgawaiD· 1 shared Chrysothemis C. BrowniD· 1 shared Daichi SadatoiD· 1 shared Hayato HiraiiD· 1 shared

Activity by Year

2019-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

Akinori EndoORCID

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5 papers

Recent·Most cited

Runx/Cbfβ regulates the development of tolerogenic Thetis cells

Chihiro Ogawa, Chengcheng Zou, Yoselin A. Paucar Iza, Motoi Yamashita, Tyler Park, Junji Harada, Naoko Satoh‐Takayama, Masahiko Kuroda, Chrysothemis C. Brown, Ichiro Taniuchi

This study identifies Runx/Cbfβ transcriptional factor complexes as regulators of Thetis cell subset development and Rorγt+ pTreg cell induction.

Nature Immunology · Jun 19, 2026Peer-reviewedImmunology

BRCA2 loss triggers a downward spiral of genomic instability via ROS-dependent metabolic collapse

Hayato Hirai, Tomohiro Iguchi, Kenji Kitajima, Kosuke Yamazaki, Daichi Sadato, Kosuke Tanegashima, Yutaka Kanoh, Hiroko Masuda, Saori Wakasa, Manami Sano, Ryotaro Kawasumi, Kosei Yamada, Shintaro Yamada, Akinori Endo, Noriko Nakatsugawa, , Hiroyuki Sasanuma

This paper shows BRCA2 loss causes genomic instability through ROS-dependent metabolic collapse, highlighting the role of glutathione metabolism and PARP inhibitors in cell death.

bioRxiv · May 21, 2026 · PreprintCell Biology

Cbfb2 gene dosage programs the differential lymphoid lineage developmental potential of fetal and adult hematopoietic progenitors

Alyssa Berthelette, Kaelie Newell, Quan M Phan, Ichiro Taniuchi, Joonsoo Kang, Michela Frascoli

This study shows that Cbfb2 gene dosage regulates the developmental potential of hematopoietic progenitors, enabling fetal-like lymphoid lineage generation in adults.

bioRxiv · Mar 5, 2026 · PreprintImmunology

Genome organization by SATB1 binding to base-unpairing regions (BURs) provides scaffold for SATB1-regulated gene expression

Yoshinori Kohwi, Xianrong Wong, Mari Grange, Tom Sexton, Hunter W. Richards, Yohko Kitagawa, Shimon Sakaguchi, Ya‐Chen Liang, Cheng‐Ming Chuong, Vladimir A. Botchkarev, Ichiro Taniuchi, Karen L. Reddy, Terumi Kohwi-shigematsu

The paper identifies SATB1's role in genome organization through direct binding to BURs, linking chromatin structure to cell type-specific gene expression.

eLife · Oct 2, 2025Peer-reviewedGenomics

Anterior Cleft Palate due to Cbfb deficiency and its rescue by folic acid

Safiye Esra Sarper, Toshihiro Inubushi, Hiroshi Kurosaka, Hitomi Ono Minagi, Yuka Murata, Koh-ichi Kuremoto, Takayoshi Sakai, Ichiro Taniuchi, Takashi Yamashiro

The paper shows that Cbfb is essential for anterior palatogenesis and that folic acid rescues cleft palate by restoring Stat3 phosphorylation and Tgfb3 expression in vitro.

Disease Models & Mechanisms · Jun 1, 2019Peer-reviewedDevelopmental Biology