Atomic Structure and Phospholipid Binding Properties of the Francisella Type VI Secretion System Effector Protein PdpC
Xiaoyu Liu, Daniel L. Clemens, Bai‐Yu Lee, Xian Xia, Hongcheng Fan, Kaelyn Y. Feng, Marcus A. Horwitz, Z. Hong Zhou
The paper determines the cryoEM structure of PdpC, an effector protein from Francisella tularensis, and shows its binding to host phospholipids, revealing insights into its role in virulence.
bioRxiv · May 8, 2025 · PreprintMicrobiology