Upstream open reading frames buffer translational variability during Drosophila evolution and development
Yuanqiang Sun, Yuange Duan, Peixiang Gao, Chenlu Liu, Kaichun Jin, Shengqian Dou, Wenxiong Tang, Hong Zhang, Jian Lü
This study shows uORFs reduce translational variability in Drosophila across development and evolution, with buffering effects observed in gene expression and phenotypes.
bioRxiv · Nov 13, 2024Evolutionary Biology