Jian Lü

Comparative population genomics reveals adaptive convergence in two Drosophila species across global environments

This study identifies convergent adaptive genes in two Drosophila species across global environments, showing shared evolutionary responses to environmental pressures.

Upstream open reading frames dynamically modulate CLOCK protein translation to regulate circadian rhythm and sleep

This study shows that uORFs in the Clock gene regulate circadian rhythm and sleep by modulating CLK protein translation in Drosophila.

Upstream open reading frames buffer translational variability during Drosophila evolution and development

This study shows uORFs reduce translational variability in Drosophila across development and evolution, with buffering effects observed in gene expression and phenotypes.

Genome-wide impact of codon usage bias on translation optimization in Drosophila melanogaster

This study examines the impact of codon usage bias on translation efficiency and error rates in Drosophila melanogaster using ribosome profiling and mass spectrometry data.