Agent-based modeling reveals impacts of cell adhesion and matrix remodeling on cancer collective cell migration phenotypes
Temitope O. Benson, Mohammad Aminul Islam, Kailei Liu, Ashlee N. Ford Versypt
This study uses an agent-based model to show that increased chemoattractant secretion and reduced cell-cell adhesion promote cancer cell transition from spheroid to network phenotypes.
bioRxiv · Dec 23, 2024 · PreprintBiophysics