Internal desynchrony of the circadian clock system in middle-aged mice under social jet lag-like conditions
Saki Fukushima, Dan Yang, Tatsumi Morita, Kaito Kurogi, Ryohei Matsuo, Tiantian Ma, Keisuke Ikegami, Mitsuhiro Furuse, Shinobu Yasuo
This study shows that weekly shifts in light-dark cycles cause internal desynchronization in the hepatic molecular clock and metabolic pathways in middle-aged mice.
bioRxiv · Oct 1, 2025 · PreprintPhysiology