Author

Kamei Au

University College London

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Neuroscience· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

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Saad B. HannaniD· 1 shared Trevor G. SmartiD· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperNeuroscience

Saad B. HannanORCID

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1 paper

Recent·Most cited

Inhibitory neurosteroid reverses the dendritic spine disorder caused by gain-of-function GABAAR epilepsy variants

Saad B. Hannan, Kamei Au, Trevor G. Smart

This study identifies gain-of-function GABAAR variants in GABRA1 that increase GABAergic signaling and reduce dendritic spine density, which can be reversed by the neurosteroid pregnenolone sulphate.

bioRxiv · Dec 8, 2021 · PreprintNeuroscience