Glutamate NMDA receptors containing GluN2C subunit relay the reward signal of the ventral tegmental area upon dorsal raphe stimulation
Giovanni Hernández, Willemieke M. Kouwenhoven, Emmanuelle Poirier, karim lebied, Daniel Lévesque, Pierre-Paul Rompré
The paper identifies GluN2C NMDA receptors in the VTA as critical for relaying reward signals from DR stimulation, showing reduced reward with GluN2C downregulation and increased reward with NMDA antagonist.
PLoS ONE · Nov 6, 2023Peer-reviewedNeuroscience