Structural Basis for Nucleobase Activation by the Adenine DNA Glycosylase MutY
L. Peyton Russelburg, Merve Demir, Karina Cedeno, Sheila S. David, Martin P. Horvath
This study investigates the role of catalytic Glu43 in MutY's mechanism by analyzing variants and showing their impact on substrate conformation and product formation.
ChemBioChem · Jun 11, 2026Peer-reviewedBiochemistry