Disruption of undecaprenyl phosphate recycling suppresses ampC beta-lactamase induction in Pseudomonas aeruginosa
Karina Klycheva, Joël Gyger, Mélissa Frund, Gabriel Torrens, Felipe Cava, Coralie Fumeaux
This paper shows that disrupting undecaprenyl phosphate recycling via DedA4 deletion reduces AmpC beta-lactamase production and beta-lactam resistance in P. aeruginosa.
PLoS Pathogens · Oct 21, 2025Peer-reviewedMicrobiology