Memory destabilization and reconsolidation dynamically regulate the PKMζ maintenance mechanism
Matteo Bernabo, Josué Haubrich, Karine Gamache, Karim Nader
The paper investigates how PKMζ levels change during memory destabilization and reconsolidation, showing transient reduction followed by renewal, and identifies NMDA receptor activation as necessary for memory vulnerability to PKMζ-antisense.
Journal of Neuroscience · Apr 22, 2021Peer-reviewedNeuroscience