Cell-free chromatin particles damage genomic DNA of healthy cells via an ROS-independent mechanism
Karishma Jain, Gorantla Venkata Raghuram, Relestina Lopes, Naveen Kumar Khare, Snehal Shabrish, Indraneel Mittra
The paper shows that cell-free chromatin particles cause genomic DNA damage in an ROS-independent manner, suggesting new therapeutic targets for aging and degenerative diseases.
bioRxiv · Aug 16, 2024 · PreprintCell Biology