Deoxysphingolipids activate cGAS-STING1 and enhance antitumor immunity
Suchandrima Saha, Fabiola Noelia Velazquez, Fatemeh Dehpanah, Brianna L. Bergfalk, Samantha C. Mulkeen, Karissa J. Lopez, 毛存贵, David C. Montrose
This study shows deoxySLs activate cGAS-STING1 and enhance antitumor immunity by promoting immune cell infiltration and suppressing tumor growth.
Cell Reports · Oct 1, 2026Peer-reviewedCancer Biology