Author

Karmella Haynes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

David A. Brafman· 1 shared Josh P. Cutts· 1 shared Rene M. Daer· 1 shared

Activity by Year

2016-2016 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperSynthetic Biology

David A. Brafman

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1 paper

Recent·Most cited

The impact of chromatin dynamics on Cas9-mediated genome editing in human cells

Rene M. Daer, Josh P. Cutts, David A. Brafman, Karmella Haynes

This study investigates how chromatin dynamics affect Cas9-mediated genome editing in human cells and shows that closed chromatin inhibits editing, which can be reversed to restore efficiency.

bioRxiv · Aug 25, 2016Synthetic Biology