Author

Karsten B. Sieber

GlaxoSmithKline (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Assay:GWAS summary statistics· 2 Approach:statistical model· 2 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Organism:human· 1

Frequent Co-Authors

Cong GuoiD· 2 shared Mark R. Hurle· 2 shared Aidan MacNamaraiD· 1 shared Alex GutteridgeiD· 1 shared Ali Amin Al OlamaiD· 1 shared Astrid J.M. YeoiD· 1 shared Jorge Esparza-Gordillo· 1 shared Kijoung S Song· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Cong GuoORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Network and pathway expansion of genetic disease associations identifies successful drug targets

Aidan MacNamara, Nikolina Nakić, Ali Amin Al Olama, Cong Guo, Karsten B. Sieber, Mark R. Hurle, Alex Gutteridge

This study uses genetic associations from GWAS and network propagation to identify drug targets enriched for clinical success.

Scientific Reports · Dec 1, 2020Peer-reviewedGenetics

Identification of putative effector genes across the GWAS Catalog using molecular quantitative trait loci from 68 tissues and cell types

Cong Guo, Karsten B. Sieber, Jorge Esparza-Gordillo, Mark R. Hurle, Kijoung S Song, Astrid J.M. Yeo, Laura M. Yerges-Armstrong, Toby Johnson, Matthew R. Nelson

The paper introduces PICCOLO, a method to identify colocalized genes between GWAS and xQTLs, finding 30% of associations have at least one colocalized gene-xQTL.

bioRxiv · Oct 17, 2019 · PreprintGenetics