Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development
Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, Gianluca Amadei, Yonatan Stelzer, Magdalena Zernicka‐Goetz
This paper develops an in vitro mouse ESC model that recapitulates embryonic and extraembryonic development from day 5.5 to 8.5, showing similar transcriptional programs to natural embryos.
bioRxiv · Aug 1, 2022 · PreprintDevelopmental Biology