The trypanosome Variant Surface Glycoprotein mRNA is stabilized by an essential unconventional RNA-binding protein
Larissa Mélo do Nascimento, Franziska Egler, Katharina Arnold, Nina Papavisiliou, CHRISTINE E. CLAYTON, Esteban Erben
This study identifies CFB2 as an essential RNA-binding protein that stabilizes VSG mRNA in trypanosomes, crucial for antigenic variation and cell survival.
bioRxiv · Oct 8, 2020 · PreprintMolecular Biology