CHRISTINE E. CLAYTON

The paper identifies sequences and proteins influencing trans splicing in Trypanosoma brucei and shows evolutionary conservation of SR-domain and PTB functions.

The paper investigates the roles of EIF4E2, EIF4E5, and EIF4E6 in Trypanosoma brucei, finding that EIF4E2 maintains S-phase mRNA abundance and is involved in mRNA stabilization.

This study shows that DRBD18 in Trypanosoma brucei regulates mRNA polyadenylation and 3-UTR length by preventing splicing factor recognition of polypyrimidine tracts and promoting mRNA export.

The paper identifies multiple regulatory sequences in the 3'-untranslated regions of mRNAs that control bloodstream-form-specific gene expression in Trypanosoma brucei.

This study investigates the role of the EIF4E1-4EIP cap-binding complex in translation repression in Trypanosoma brucei, showing that 4EIP stabilizes EIF4E1 and recruits TUT3, but NOT complex may be involved in 4EIP function.

The paper shows DRBD18 regulates RBP10 mRNA processing and export in Trypanosoma brucei by interacting with its 3-UTR, affecting mRNA stability and localization.

The paper describes two new Trypanosoma brucei brucei strains with minimal in vitro passage and reports gene copy-number changes associated with culture adaptation.

This study identifies CFB2 as an essential RNA-binding protein that stabilizes VSG mRNA in trypanosomes, crucial for antigenic variation and cell survival.

The paper identifies a novel RNA-binding protein complex in Trypanosoma brucei and shows its role in mRNA translation and quality control.

This study shows that PUF3 is not essential for Trypanosoma brucei growth or differentiation in vitro but may have a role in the invertebrate host or gene expression regulation.

The paper identifies PBP1-associated proteins in Trypanosoma brucei, showing their roles in mRNA stabilization and translation initiation complex recruitment.

This paper identifies ERBP1 and ERBP2 as ER-associated mRNA-binding proteins in T. brucei that interact and bind ribosomal protein mRNAs, but not secreted protein mRNAs or stress granules.

This study identifies ZC3H20 and ZC3H21 as mRNA stabilizing factors in Trypanosoma brucei, showing they regulate membrane and mitochondrial protein mRNAs during developmental transitions.

This study shows that 4EIP suppresses mRNA translation in Trypanosoma brucei and is required for differentiation to stumpy forms.

This study shows that heat shock in Trypanosoma brucei affects mRNA translation and granule formation, with some mRNAs remaining active and promoting differentiation to mammalian-infective forms.