An early mechanosensitive window in bone fracture healing shapes long-term repair
Liesbeth Ory, Gabriele Nasello, Edoardo Borgiani, Tom Verbraeken, Kathleen Bosmans, Carla Geeroms, Inge Van Hoven, Elena Nefyodova, Claire Chabot, Liesbet Geris, Przemko Tylżanowski
This study shows that early mechanical environment during bone fracture healing determines repair trajectory, with optimal stiffness applied early enhancing regeneration.
bioRxiv · Sep 28, 2026 · PreprintBioengineering