Liesbet Geris

This study shows that early mechanical environment during bone fracture healing determines repair trajectory, with optimal stiffness applied early enhancing regeneration.

This study compares bioreactor loading protocols to finite element models of the human knee to assess their ability to replicate native joint mechanics.

This paper develops a multiscale model linking tissue mechanics, cellular forces, and gene regulation in articular cartilage to study OA pathophysiology.

This study shows that cell culture dimensionality affects intracellular crowding, which influences cell fate through a mechano-metabolic signaling pathway, improving chondrogenic differentiation in microtissue cultures.

The paper describes the development and evaluation of an agentic framework using LLMs to explore molecular interaction maps through user-driven prototyping and testing.

This study assesses inter-laboratory variability in mechanical property characterization of porcine aorta through two testing rounds, highlighting persistent discrepancies despite protocol standardization.

The paper integrates multi-omics data to explore host-pathogen interactions in severe Pseudomonas aeruginosa infection, identifying key molecular mechanisms and interactions.

The paper integrates ten scRNA-seq datasets to create a limb skeletal cell atlas covering development to adulthood, identifying 39 cell states and enabling cell-cell communication and perturbation studies.

This study combines in silico and in vitro approaches to identify drug targets for osteoarthritis by modeling chondrocyte phenotype transitions and validating predictions in cell lines.