Revisiting The Role of Notch in Nephron Segmentation: Notch is required for proximal, not distal fate selection during mouse and human nephrogenesis
Kathryn Duvall, Lauren Bice, Alison J. Perl, Naomi Pode‐Shakked, Praneet Chaturvedi, Raphael Kopan
The paper investigates Notch signaling's role in nephron segmentation, finding it promotes proximal fate selection while not affecting distal fate in mouse and human kidney development.
bioRxiv · Dec 14, 2021 · PreprintDevelopmental Biology