Microsatellite instability as a tool to diagnose genome instability in CHO cell culture
Dylan G. Chitwood, Qinghua Wang, Kathryn Elliott, Aiyana Bullock, Dwon Jordana, Zhijang Li, Cathy H. Wu, Sarah W. Harcum, Christopher A. Saski
This study investigates the effects of elevated ammonia on genome instability in CHO cells, identifying de novo mutations and microsatellite instability as biomarkers for genome stability.
bioRxiv · Oct 29, 2019 · PreprintGenomics