Author

Qinghua Wang

University of DelawareORCID 0000-0002-4289-5813Unclaimed ORCID profile · follow to get notified of new preprints

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Qinghua Wang2 papers

Biology Disciplines

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Bioinformatics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Gang XuiD· 2 shared Jianpeng MaiD· 2 shared Aiyana Bullock· 1 shared Cathy H. WuiD· 1 shared Christopher A. SaskiiD· 1 shared Dwon Jordana· 1 shared Dylan G. Chitwood· 1 shared Kathryn Elliott· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

Gang XuORCID

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3 papers

Recent·Most cited

BioinformaticsBriefings in BioinformaticsPeer-reviewedSep 22, 2023

OPUS-Fold3: a gradient-based protein all-atom folding and docking framework on TensorFlow

Gang Xu, Zhenwei Luo, Ruhong Zhou…·Jianpeng Ma

OPUS-Fold3 is a gradient-based protein folding and docking framework that generates accurate 3D structures under specified constraints, outperforming pyRosetta in side-chain modeling.

1 citation

protein structuredeep learning

BioinformaticsJournal of Chemical Theory and ComputationPeer-reviewedFeb 22, 2023

OPUS-Mut: studying the effect of protein mutation through side-chain modeling

Gang Xu, Qinghua Wang, Jianpeng Ma

OPUS-Mut improves side-chain modeling for mutation effect analysis, showing good agreement with experimental results and correlating structural shifts with functional changes.

12 citations

protein structuredeep learning

GenomicsbioRxivPreprintOct 29, 2019

Microsatellite instability as a tool to diagnose genome instability in CHO cell culture

Dylan G. Chitwood, Qinghua Wang, Kathryn Elliott…·Christopher A. Saski

This study investigates the effects of elevated ammonia on genome instability in CHO cells, identifying de novo mutations and microsatellite instability as biomarkers for genome stability.

DOI 10.1101/823252

mousewhole-genome sequencing