Altered hematopoietic system and self-tolerance in Bardet-Biedl Syndrome
Oksana Tsyklauri, Veronika Niederlová, Elizabeth L. Forsythe, Avishek Prasai, Ales Drobek, Petr Kašpárek, Kathryn Sparks, Zdeněk Trachtulec, Jan Procházka, Radislav Sedláček, Philip L. Beales, Martina Huranová, Ondřej Štěpánek
This study investigates immune and hematopoietic system alterations in Bardet-Biedl Syndrome patients and a mouse model, finding increased autoimmune disease incidence, elevated white blood cell counts, and B cell abnormalities.
EMBO Reports · Jan 11, 2021Peer-reviewedGenetics