Delineation of the Complete Reaction Cycle of a Natural Diels-Alderase
Laurence Maschio, Catherine R. Back, Jawaher Alnawah, James I. Bowen, Samuel T. Johns, Sbusisiwe Z. Mbatha, Li-Chen Han, Nicholas R. Lees, Katja Zorn, James E. M. Stach, Martin A. Hayes, Marc W. van der Kamp, Christopher R. Pudney, Steven G. Burston, Christine L. Willis, Paul R. Race
This study provides a molecular description of the complete reaction cycle of the natural Diels-Alderase AbyU using X-ray crystallography, kinetics, and computational simulations.
bioRxiv · Apr 18, 2024Biochemistry