Steven G. Burston

The paper identifies and characterizes intramolecular isopeptide bonds in protein domains across organisms, revealing their structural and functional significance.

This study identifies HTRA1 as a non-autonomous protein quality control factor that inhibits tau aggregate propagation by interfering with multiple steps of the spreading process.

This study provides a molecular description of the complete reaction cycle of the natural Diels-Alderase AbyU using X-ray crystallography, kinetics, and computational simulations.