TGF-β signaling promotes the expression of proviral circular RNA ciTRAN in HIV-1 infection
Aditi Choudhary, Katyayani Mallick, Rishikesh Dalavi, Ajit G. Chande
The paper shows that TGF-β signaling, triggered by HIV-1 Vpr, increases ciTRAN expression through SMAD2/3 recruitment to the SMARCA5 promoter.
PLoS Pathogens · Jul 9, 2025Peer-reviewedMicrobiology