Modeling interaction between focal cerebral ischemia and Alzheimer`s Disease Pathology in an APP/PS1 Mouse Model
Paxton Waits, P. Anthony Otero, M. M. Zimmerly, Vidhaath Vedati, Kavi J. Shah, James E. Orfila, Paco S. Herson
This study develops a novel mouse model to investigate the interaction between focal cerebral ischemia and Alzheimer's Disease pathology, finding an additive effect on memory and hippocampal function.
bioRxiv · Sep 5, 2025 · PreprintNeuroscience