Paco S. Herson

This study develops a novel mouse model to investigate the interaction between focal cerebral ischemia and Alzheimer's Disease pathology, finding an additive effect on memory and hippocampal function.

This study identifies sex- and circuit-specific amygdala dysfunction after global cerebral ischemia in mice, linked to enhanced calcium signaling in male survivors.

This study shows that endogenous recovery of hippocampal long-term potentiation (LTP) after global cerebral ischemia in juvenile female mice depends on neuroinflammation and sex hormones, differing from males and adults.

The paper shows that TRPM2-CaMKII signaling enhances GABAergic synaptic inhibition after ischemia, leading to E/I imbalance and potential therapeutic targets for cognitive recovery.

This study uses scRNA-seq to analyze oligodendrocyte gene expression changes in a neonatal mouse model of stroke, identifying a reactive subset that may be a target for white matter repair.

This study shows that short-term CaMKII inhibition with tatCN19o does not erase existing memories and is neuroprotective in non-rodents.

This study shows that CaV3.1 T-type calcium channels in the dorsal subiculum regulate burst firing, synaptic plasticity, and spatial memory in mice.

This study examines cofilin-actin rod formation in different mouse models of brain ischemia and finds that rod formation varies with ischemic conditions and reperfusion timing.