Kinetic organization of the genome revealed by ultra-resolution, multiscale live imaging
Joo Lee, Liangfu Chen, Simon Gaudin, Kavvya Gupta, Andrew J. Spakowitz, Alistair Nicol Boettiger
This paper introduces TRACK-IT, a live imaging technique that reveals rapid, cohesin-dependent genomic motion across multiple scales, challenging previous assumptions about genome organization.
bioRxiv · Mar 27, 2025 · PreprintBiophysics