Transcriptomics-informed pharmacology identifies epigenetic and cell cycle regulators as enhancers of AAV production
Joshua M. Tworig, Francis Grafton, Kaylin Fisher, Markus Hörer, Christopher A. Reid, Mohammad A. Mandegar
This study identifies epigenetic and cell cycle regulators that enhance AAV production by analyzing transcriptomic responses in cell lines with varying production capacities.
Molecular Therapy — Methods & Clinical Development · Nov 18, 2024Peer-reviewedCell Biology