Genome-Wide Profiling of tRNA Using an Unexplored Reverse Transcriptase with High Processivity
Yuko Nakano, Howard Gamper, Henri McGuigan, Sunita Maharjan, Zhiyi Sun, Keerthana Krishnan, Erbay Yigit, Nan‐Sheng Li, Joseph A. Piccirilli, Ralph E. Kleiner, Nicole M. Nichols, Ya‐Ming Hou
The paper introduces Induro-tRNAseq, a method using a high-processivity reverse transcriptase to profile tRNA modifications, revealing novel proline codon modifications in humans.
bioRxiv · Dec 9, 2023 · PreprintGenomics