The GspCD-dependent type II secretion system drives necrotizing soft tissue infection by Aeromonas hydrophila
Yuka Tonosaki, Kohei Yamazaki, Shota Owada, Kei Yamaguchi, Takashige Kashimoto
This study shows that the GspCD-dependent type II secretion system in Aeromonas hydrophila drives necrotizing soft tissue infection by facilitating extracellular protein secretion, virulence factor release, and bacterial dissemination in a mouse model.
bioRxiv · May 4, 2026 · PreprintMicrobiology