Proteogenomic annotation of the Chinese hamster reveals extensive novel translation events and endogenous retroviral elements
Shangzhong Li, Seong Won Cha, Kelly Heffner, Deniz Baycın Hızal, Michael A. Bowen, Raghothama Chaerkady, Robert Norman Cole, Vijay Tejwani, Prashant Kaushik, Michael A. Henry, Paula Meleady, Susan T. Sharfstein, Michael J. Betenbaugh, Vineet Bafna, Nathan E. Lewis
The paper improves genome annotation for Chinese hamster by integrating RNA-Seq, proteomics, and Ribo-Seq, identifying new proteins and translational events, and addressing retroviral contamination in CHO cell lines.
Journal of Proteome Research · Apr 25, 2019Peer-reviewedBioinformatics