Transcription-dependent DNA methylation at the imprinted Zrsr1-DMR
Keiichiro Joh, Fumikazu Matsuhisa, Shuji Kitajima, Kenichi Nishioka, Ken Higashimoto, Hitomi Yatsuki, Tomohiro Kono, Haruhiko Koseki, Hidenobu Soejima
The paper shows that transcription of Commd1 through the Zrsr1-DMR is required for its methylation, establishing a transcription-dependent mechanism for imprinted gene regulation.
Epigenetics & Chromatin · Jun 6, 2018Peer-reviewedMolecular Biology