High-resolution phenotypic landscape of the RNA Polymerase II trigger loop
Chenxi Qiu, Olivia C. Erinne, Jui Dave, Ping Cui, Huiyan Jin, Nandhini Muthukrishnan, Leung K. Tang, Sabareesh Ganesh Babu, Kenny C. Lam, Paul J. Vandeventer, Ralf Strohner, Jan Van den Brulle, Sing-Hoi Sze, Craig D. Kaplan
The paper quantitatively phenotypes nearly all single-residue variants of the RNA Polymerase II trigger loop in Saccharomyces cerevisiae to uncover functional classes and their roles in transcription.
bioRxiv · Aug 14, 2016Molecular Biology