Increased Colonic Expression of ACE2 Associates with Poor Prognosis in Crohn's disease
Takahiko Toyonaga, Kenza C. Araba, Meaghan M. Kennedy Ng, Benjamin P. Keith, Elisabeth A. Wolber, Caroline Beasley, Erin C. Steinbach, Matthew R. Schaner, Animesh Jain, Millie D. Long, Edward L. Barnes, Hans H. Herfarth, Kim L. Isaacs, Jonathan J. Hansen, Muneera Rehana Kapadia, , Shehzad Z. Sheikh
The paper finds that increased colonic ACE2 expression in Crohn's disease patients is associated with a higher risk of surgery within 5 years.
bioRxiv · Nov 24, 2020 · PreprintGenomics