Single-cell analysis of colonic epithelium reveals unexpected shifts in cellular composition and molecular phenotype in treatment-naiïve adult Crohn's disease
Matt Kanke, Meaghan M. Kennedy Ng, Sean V. Connelly, Matthew R. Schaner, Michael T. Shanahan, Elisabeth A. Wolber, Caroline Beasley, Grace Lian, Animesh Jain, Millie D. Long, Edward L. Barnes, Hans H. Herfarth, Kim L. Isaacs, Jonathan J. Hansen, Muneera Rehana Kapadia, , Praveen Sethupathy
The paper uses single-cell analysis to compare colonic epithelial cells in Crohn's disease and control patients, revealing shifts in cell composition and gene expression patterns.
bioRxiv · Jan 13, 2021 · PreprintGenomics