Benjamin P. Keith

This study develops a multi-omics framework to identify biomarkers of inhaled drug-induced lung toxicity using spatial transcriptomics, proteomics, and histopathological data.

This study maps spatial transcriptomes of human and mouse pulmonary fibrosis to identify fibrotic niches and differences in alveolar regeneration.

The paper finds that increased colonic ACE2 expression in Crohn's disease patients is associated with a higher risk of surgery within 5 years.

The paper shows that disease-associated genes are often the more evolutionarily constrained duplicates, challenging the compensatory model and introducing a new disease prediction model.

This study identifies miR-31 as a marker that stratifies Crohn’s disease patients into two subtypes with distinct clinical outcomes.