Induced neural progenitor cells and iPS-neurons from major depressive disorder patients show altered bioenergetics and electrophysiological properties
Julian Triebelhorn, Iseline Cardon, Kerstin Kuffner, Stefanie M. Bader, Tatjana Jahner, Katrin Meindl, Tanja Rothhammer-Hampl, Markus J. Riemenschneider, Konstantin Drexler, Mark Berneburg, Caroline Nothdurfter, André Manook, Christoph Brochhausen, Thomas C. Baghai, Sven Hilbert, , Christian H. Wetzel
This study investigates mitochondrial dysfunction and bioenergetic changes in induced neural progenitor cells and iPS-neurons from MDD patients compared to controls.
Molecular Psychiatry · Jun 22, 2022Peer-reviewedNeuroscience