Performance of the 10X Genomics Flex Single-Cell Sequencing Assay and its Application to Overcome Challenges in Clinical Trial Samples
Martina Antoniolli, Llucia Albertí Servera, Kerstin Paetzold, Stephan Schmeing, Carmen S. M. Yong, Sina Nassiri, Tamara Hüsser, Michael A. Cannarile, Marina Bacac, Emilio Yángüez, Steffen Dettling
The paper compares scRNA-seq protocols for clinical trial samples, finding that GEM-X Flex with chop-fix outperforms standard protocols and snRNA-seq in fixed tissue and FFPE blocks.
bioRxiv · Mar 9, 2026 · PreprintGenomics