Stephan Schmeing

The paper compares scRNA-seq protocols for clinical trial samples, finding that GEM-X Flex with chop-fix outperforms standard protocols and snRNA-seq in fixed tissue and FFPE blocks.

Gapless improves genome assemblies using low-coverage long reads by combining scaffolding, gap filling, and assembly correction in a single tool.

This paper meta-analyzes single-cell method benchmarks to identify challenges in extensibility, interoperability, and reproducibility.

ReSeq generates realistic Illumina sequencing data by incorporating systematic errors and coverage models to improve performance evaluations of computational tools.

The paper identifies a Y-linked gene, MoY, essential for male sex determination in medflies and shows its conservation across multiple fruit fly species, enabling potential genetic control strategies.