Hi-GREx: A 3D Genome Guided Framework for enhancing Gene Expression Prediction Using Hi-C Selected Distal SNPs
Ketki Joshi, Min Chen, Zhenyu Xuan
The paper introduces Hi-GREx, a method using Hi-C data to select long-distance SNPs for improved gene expression prediction, outperforming traditional TWAS approaches.
bioRxiv · Sep 26, 2025 · PreprintBioinformatics