Protein Phosphatase 1 activity controls a balance between collective and single cell modes of migration
Yujun Chen, Nirupama Kotian, George F. Aranjuez, Lin Chen, C. Luke Messer, Ashley Burtscher, Ketki Sawant, Damien Ramel, Xiaobo Wang, Jocelyn A. McDonald
This study identifies Protein Phosphatase 1 (Pp1) as a regulator of collective versus single cell migration in Drosophila border cells by controlling cell cohesion and actomyosin contractility.
eLife · May 5, 2020Peer-reviewedDevelopmental Biology