Novel Replication Stress-Associated High-Grade Serous Ovarian Cancer Models Recapitulate Diverse Tumour Ecosystems and Enable Preclinical Studies
Violaine Pourcel, Zacharie Drouin, Emile Létourneau, Zoé Gerber, Kevin-Row Malkoun, Dominique Jean, Morgane Placet, Marilyne Labrie
This study develops HGSC models with RS-associated mutations to explore diverse tumour ecosystems and therapeutic responses.
bioRxiv · Sep 30, 2026 · PreprintCancer Biology