A Multi-Modal Deep Learning Framework with Both Sequence and Structure for Tumor Antigens Prediction
Ruofan Jin, Jingxuan Ge, Guanqiao Zhang, Ziyan Deng, Kim Hsieh, Tingjun Hou, Ruhong Zhou
MultiTAP improves tumor antigen immunogenicity prediction by integrating sequence and structure features with an attention mechanism, outperforming existing models across diverse HLA phenotypes.
bioRxiv · Nov 6, 2024 · PreprintBiophysics